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The role of the Consultative and Diagnostic Centre «Healthy Nutrition» in the diagnosis and nutritional prevention of non-communicable diseases

AbstractIn a consultative and diagnostic center «Healthy Nutrition» of Institute of Nutrition the nutritional status of 3500 patients (mean age 48,4±0,3 years) living in the Moscow region, using a system Nutritest IP-3, including genomic analysis has been examined. In the analysis of dietary intake by an average review, increased energy intake due to excess intake of the total (44,2% energy) and saturated fat (13,6%) has been shown. 30,0% of patients were overweight and 34,1% were obese. Osteopenia was detected in 31,0% of men and 25,0% women, osteoporosis – 20,9% and 30,3%, respectively. Analysis of the results of biochemical studies revealed increased cholesterol in 68,7% of patients, LDL cholesterol – at 63,9%, triglycerides – at 22,5%, glucose – at 29,4%. The frequency of the occurrence of risk alleles of genes associated with the development of obesity and type 2 diabetes mellitus was: 47,8% – for the polymorphism rs9939609 (FTO gene), 8,3% – for polymorphism rs4994 (gene ADRB3), 60,2% – for the polymorphism rs659366 (gene UCP2), 36,6% – for the rs5219 polymorphism in the gene of ATP-dependent potassium channel.

Keywords:dietary intake, nutritional status, hypercholesterolemia, hyperglycemia, bone density, gene polymorphism


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