Influence of combined lacto vegetarian diet and selective beta-blocking agents on clinical and metabolic indexes in patients with coronary heart disease
AbstractClinical, hemodynamic and metabolic parameters were investigated for 42 patients with coronary heart disease, after myocardial infarct, recieved selective β-adrenoblockers. Patients were divided in two groups. The first group (24 patients) were given methoprolol (50 mg/daily) and antiatherogenic lacto vegetarian diet, the second (18 patients) – methoprolol (50 mg/daliy) and standard mixed antiatherogenic diet. After the treatment, positive changes clinical and gemodynamic parameters were observed in both groups of patients. Among the clinical symptoms, a more pronounced decrease in blood pressure in the patients on vegetarian diet and a more significant increase in their exercise tolerance. The level of total cholesterol on the serum of blood decreased by 16%, low-density lipoproteins cholesterol decreased by 18%, the atherogenic coefficient (KA) decreased by 31%, only in vegetarian group. High-density lipoprotein cholesterol increased in vegetarian group, by 14% and decreased in control group. Balanced antiatherogenic lacto vegetarian diet in patients with coronary heart disease prevents the hyperlipedemic effect caused by the selective β-adrenoblockers and it is an agent for preventing its negative effect on lipid metabolism.
Keywords:lacto vegetarian diet, coronary heart disease, selective beta-blocking agents, hyperlipidemia, lipid spectrum, rehabilitation