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The influence of probiotic fermented milk product on colon microbiota, hematological parameters and cell immunity in rats

AbstractInfluence of probiotic fermented milk product on the intestinal microbiota, hematological parameters and immune status of the experiment in vivo at Wistar rats was studied. It was shown, that entering of probiotic strains of Bifidobacterium bifidum 791, Bifidobacterium longum B-379M and Lactobacillus acidophilus NK1 и Streptococcus thermophilus in composition fermented milk products in the total quantity of 2,1107 CFU/ sm3 in digestive tract within three weeks has a positive influence on the resident of colon microbiota. Significant increasing of population levels of Вifidobacterium, Enterobacteriaceae with normal biochemical properties, registered a strong tendency to increase the content of Lactоbacteria, which led to a decreasing the number of potential pathogenic transient flora with pathogenic factors. Monitoring of body mass in experimental animals has shown that including of fermented milk product with probiotic strains in diet has a positive influence on the feed uptake. Probiotic properties of the product also have stimulated effect on the immune status of the rat: improvements in cell immunity (increasing the relative amount of T-helper cells, immuneregulatory index) and hematological parameters (increase of the average concentration of hemoglobin in erythrocyte).

Keywords:probiotic fermented milk product, colon microbiota, bifidobacterium, cell immunity


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